描 述:Ac-WEHD-CHO, a very potent reversible inhibitor of caspase-1 (ICE). It bears the optimal tetrapeptide recognition motif for this enzyme. With a Ki of 56 pM it belongs to the most potent reversible, peptide-based inhibitors described for any protease. For caspase-8 a Ki of 21.1 nM has been reported.Ac-WEHD-CHO是一種非常有效的caspase-1 (ICE)的可逆抑制劑。它具有該酶的最佳四肽識(shí)別基序。其Ki值為56 pM,屬于最有效的可逆性肽類蛋白酶抑制劑。caspase-8的Ki值為21.1 nM。