Exendin(9-39) amide
同義詞:Avexitide
分子量:3369.76
分子式:C149H234N40O47S
CAS 號:133514-43-9
產(chǎn)品描述:
Avexitide (Exendin (9-39)) 是特異競爭性的 glucagon-like peptide-1 (GLP-1) 受體拮抗劑。
體外研究:
GLP-1 plays a role in the control of fasting glucose. Avexitide (Exendin (9-39)), a truncated form of the GLP-1 agonist exendin-4, is a specific GLP-1 receptor antagonist。
體內(nèi)研究:
Continuous subcutaneous infusion of Avexitide (Exendin (9-39)) significantly raises fasting blood glucose levels in SUR-1 -/- mice without affecting glucose tolerance。
H2O 中的溶解度 : 50 mg/mL (14.84 mM; 超聲助溶)