GLP-1(7-37)
同義詞: 人胰高血糖素樣肽-1
分子量:3355.67
分子式:C151H228N40O47
CAS 號:106612-94-6
三字母:His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly
單字母:HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG
產(chǎn)品描述:
GLP-1(7-37) 是一種腸道胰島素激素,可以增強葡萄糖誘導(dǎo)的胰島素分泌。
體內(nèi)研究:
GLP-1(7-37) (0.5, 5 or 50 pmol/min/kg) infused during the second hour of a 2-hour 11-mM hyperglycemic clamp produces a dose-related enhancement of the glucose-stimulated increase in plasma insulin concentration and an increased rate of glucose infusion in rats。
Infusion of GLP-1(7-37) (5 pmol/min/kg) from 1 hour through 7 hours produces a sustained increase in plasma insulin concentration relative to levels in rats infused with vehicle in rats with maintained glucose concentration at 11 mM。