Felypressin acetate (Synonyms: PLV-2 acetate)
產(chǎn)品描述：
Felypressin vinegar (PLV-2 vinegar) 是一種非兒茶酚胺的血管收縮劑，也是一種加壓素 1 ( vasopressin 1 ) 激動劑。Felypressin vinegar 廣泛用于牙科手術(shù)中。
分子式：C46H65N13O11S2.xC2H4O2
CAS 號：914453-97-7
三字母：Cys-Phe-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bridge: Cys1-Cys6)
單字母：CFFQNCPKG-NH2 (Disulfide bridge: Cys1-Cys6)
體外研究：
苯賴加壓素是一種合成的垂體后葉激素，具有血管收縮特性，廣泛用于牙科手術(shù)。苯賴加壓素的血管收縮作用似乎是由血管平滑肌細胞的 V1 受體介導(dǎo)的
體內(nèi)研究：
Felypressin can reduce toxicity during dental procedures. Felypressin increases the diastolic blood pressure of hypertensive patients with controlled blood pressure.
Cardiovascular effects of Felypressin (240 ng/kg; intravenous injection) are studied in Wistar rats. Felypressin induces a pressor effect. Felypressin depends on V1 receptors to induce pressor and bradycardic effects, and that it produces a high relationship between bradycardia and mean arterial pressure variation depending on area postrema and central V1 receptors。
