基質(zhì)金屬蛋白酶MMP-13, Substrate
編號：157369
CAS號：1872435-02-3
三字母：Dnp-Gly-Pro-Leu-Gly-Met-Arg-Gly-Leu-NH2
描 述：Highly sensitive and selective substrate for collagenase-3 (MMP-13) with a kcat/Km value of 4.22 · 10⁶ M⁻¹s⁻¹ (pH = 7.5, T = 37 °C). The kcat/Km value of human collagenase-3 for this synthetic peptide is 1344-, 11-, and 820-fold better than that of related MMPs stromelysin-1 (MMP-3), gelatinase B (MMP-9), and collagenase-1 (MMP-1), respectively.
對膠原酶-3 (MMP-13)具有高度敏感性和選擇性的底物，kcat/Km值為4.22·10⁶M毒血癥(pH = 7.5, T = 37°C)。該合成肽的人膠原酶-3的kcat/Km值分別是相關(guān)MMPs基質(zhì)溶素-1 (MMP-3)、明膠酶B (MMP-9)和膠原酶-1 (MMP-1)的1344倍、11倍和820倍。
